Description

2-Chloro-3-Nitro-5-Bromo-6-Picoline is a high-purity, multi-functional halogenated pyridine derivative that serves as a critical building block in advanced organic synthesis. Its unique substitution pattern makes it an indispensable intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for targeted therapies.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides due to its bioactive scaffold.
• Material Science Research: Serves as a monomer or functionalizing agent for creating specialized polymers and liquid crystals.
• Ligand and Catalyst Development: Employed in the preparation of complex chelating ligands for catalytic and metal-organic framework (MOF) applications.
• Chemical Biology Probes: Utilized to synthesize molecular probes for studying enzyme mechanisms and biological pathways.
• Dye and Pigment Manufacturing: Acts as an intermediate for producing high-performance, light-fast organic dyes and pigments.

Basic Information

Product Name	2-Chloro-3-Nitro-5-Bromo-6-Picoline
CAS No.	186413-75-2
Molecular Formula	C6H4BrClN2O2
Molecular Weight	251.47 g/mol
Synonyms	2-Chloro-3-nitro-5-bromo-6-methylpyridine; 5-Bromo-2-chloro-3-nitro-6-picoline; 6-Methyl-5-bromo-2-chloro-3-nitropyridine; 2-Chloro-3-nitro-5-bromo-6-methylpyridine; 5-Bromo-2-chloro-3-nitro-6-methylpyridine; 3-Nitro-5-bromo-2-chloro-6-picoline; 2-Chloro-5-bromo-3-nitro-6-methylpyridine
EINECS	Contact for details

Quality Control

Our 2-Chloro-3-Nitro-5-Bromo-6-Picoline is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and batch-to-batch consistency. We provide comprehensive Certificates of Analysis (COA) for all shipments, detailing purity, identity, and impurity profiles. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound may be light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.