Description

5-Bromo-2-Hydroxy-3-Nitro-6-Picoline is a high-purity, multi-functional heterocyclic building block of significant importance in advanced organic synthesis. Its unique substitution pattern makes it a critical intermediate for the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors. This compound is essential for researchers and manufacturers engaged in creating active pharmaceutical ingredients (APIs), specialty chemicals, and novel materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, particularly those targeting neurological and oncological pathways.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides due to its bioactive picoline core.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in metal-catalyzed cross-coupling reactions.
• Material Science Research: Employed in the development of organic electronic materials and advanced polymers.
• Chemical Research & Development: A versatile building block for academic and industrial R&D in medicinal and synthetic chemistry.
• Dye and Pigment Intermediate: Potential use in the synthesis of specialized nitro- and bromo-substituted colorants.

Basic Information

Product Name	5-Bromo-2-Hydroxy-3-Nitro-6-Picoline
CAS No.	186413-74-1
Molecular Formula	C6H5BrN2O3
Molecular Weight	233.02 g/mol
Synonyms	5-Bromo-3-nitro-2-pyridinol; 5-Bromo-3-nitro-2(1H)-pyridinone; 5-Bromo-3-nitro-2-pyridone; 2-Hydroxy-5-bromo-3-nitropyridine; 6-Methyl-5-bromo-3-nitro-2-pyridinol; 5-Bromo-2-hydroxy-3-nitropyridine; 5-Bromo-3-nitro-2-hydroxypyridine; 2-Pyridinol, 5-bromo-3-nitro-
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-Hydroxy-3-Nitro-6-Picoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with key parameters including assay, impurity profile, and residual solvents. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply and traceability for critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); ensure containers are sealed after each use to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥97.0%
Loss on Drying	≤1.0%
Residue on Ignition	≤0.5%
Heavy Metals	≤20 ppm
Single Unknown Impurity (HPLC)	≤1.0%
Total Impurities (HPLC)	≤3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.