Description

Ethyl 3-Benzyl-3-Azabicyclo[3.1.0]Hexane-6-Carboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its unique azabicyclo[3.1.0]hexane scaffold. This compound is of significant value for its role as a key building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly those targeting the central nervous system. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents, where precise chemical structure and reliable supply are critical.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of complex drug candidates, especially those with neurological activity.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new chemical entities.
• Process Chemistry Development: Serves as a standard or starting material for scaling up API synthesis under Good Manufacturing Practice (GMP) conditions.
• Contract Research & Manufacturing (CRAM): Supplied to organizations specializing in custom synthesis and development services for the pharmaceutical industry.
• Academic Research: Utilized in university and institutional labs for studying novel synthetic methodologies and heterocyclic chemistry.

Basic Information

Product Name	Ethyl 3-Benzyl-3-Azabicyclo[3.1.0]Hexane-6-Carboxylate
CAS No.	186376-30-7
Molecular Formula	C15H19NO2
Molecular Weight	245.32 g/mol
Synonyms	Ethyl 3-benzyl-3-azabicyclo[3.1.0]hexane-6-carboxylate; 3-Azabicyclo[3.1.0]hexane-6-carboxylic acid, 3-(phenylmethyl)-, ethyl ester; 6-(Ethoxycarbonyl)-3-benzyl-3-azabicyclo[3.1.0]hexane; Ethyl 3-benzyl-3-azabicyclo[3.1.0]hexane-6-carboxylate; 186376-30-7; 3-Benzyl-3-azabicyclo[3.1.0]hexane-6-carboxylic acid ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 3-Benzyl-3-Azabicyclo[3.1.0]Hexane-6-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports compliance with the stringent requirements of pharmaceutical development and cGMP principles where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.