Description

4-Phenyl-3,6-dihydro-2H-pyridine-1-carboxylic acid tert-butyl ester is a high-value, protected heterocyclic building block essential for advanced organic synthesis. This compound serves as a critical intermediate in the development of novel active pharmaceutical ingredients (APIs) and complex bioactive molecules. It is primarily sought after by research and development teams in the pharmaceutical, agrochemical, and fine chemical industries for constructing sophisticated nitrogen-containing scaffolds.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of potential drug candidates, particularly those targeting neurological and cardiovascular diseases.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to explore new chemical entities.
• Agrochemical Development: Serves as a building block for creating novel pesticides and herbicides with specific modes of action.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex, high-value specialty chemicals and catalysts.
• Academic & Contract Research: Utilized in university and CRO laboratories for methodological development and the exploration of new heterocyclic chemistry.

Basic Information

Product Name	4-Phenyl-3,6-dihydro-2H-pyridine-1-carboxylic acid tert-butyl ester
CAS No.	186347-72-8
Molecular Formula	C₁₆H₂₁NO₂
Molecular Weight	259.34 g/mol
Synonyms	tert-Butyl 4-phenyl-3,6-dihydro-2H-pyridine-1-carboxylate; 1-Boc-4-phenyl-1,2,3,6-tetrahydropyridine; 4-Phenyl-1,2,3,6-tetrahydropyridine-1-carboxylic acid tert-butyl ester; 1-N-Boc-4-phenyl-1,2,3,6-tetrahydropyridine; 4-Phenyl-3,6-dihydro-2H-pyridine-1-carboxylic acid 1,1-dimethylethyl ester; 1-(tert-Butoxycarbonyl)-4-phenyl-1,2,3,6-tetrahydropyridine; Boc-4-phenyl-1,2,3,6-tetrahydropyridine
EINECS	Contact for details

Quality Control

Every batch of our 4-Phenyl-3,6-dihydro-2H-pyridine-1-carboxylic acid tert-butyl ester is produced and tested under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the exacting standards required for research and development applications. A detailed Certificate of Analysis (COA) confirming identity, purity, and impurity profiles via HPLC, NMR, and other relevant techniques is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed to protect this light-sensitive compound from degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.