Description

1-Nitro-2,3,4-Trifluoro-5-(Trimethylsilyl)Benzene is a high-value, multi-functional aromatic intermediate featuring a unique combination of nitro, fluoro, and silyl substituents. This compound is critical for introducing specific functional groups and modifying electronic properties in advanced molecular architectures. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for the synthesis of novel active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of fluorinated drug candidates, particularly in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the fluorine atoms enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for electron-transport materials and fluorinated mesogens in display and lighting technologies.
• Polymer Modification: Employed to introduce fluorinated aromatic units into high-performance polymers, improving their thermal stability and chemical resistance.
• Cross-Coupling Reactions: The trimethylsilyl group acts as a versatile protecting group and can participate in silicon-based coupling methodologies.
• Organic Synthesis Research: A valuable reagent for academic and industrial R&D exploring new fluorination strategies and aromatic substitution patterns.

Basic Information

Item	Details
Product Name	1-Nitro-2,3,4-Trifluoro-5-(Trimethylsilyl)Benzene
CAS No.	186315-89-9
Molecular Formula	C9H9F3NO2Si
Molecular Weight	239.26 g/mol
Synonyms	2,3,4-Trifluoro-5-(trimethylsilyl)-1-nitrobenzene; 5-(Trimethylsilyl)-1-nitro-2,3,4-trifluorobenzene; 1-Nitro-2,3,4-trifluoro-5-(trimethylsilyl)benzene; Benzene, 1-nitro-2,3,4-trifluoro-5-(trimethylsilyl)-; (2,3,4-Trifluoro-5-nitrophenyl)trimethylsilane
EINECS	Contact for details

Quality Control

Our 1-Nitro-2,3,4-Trifluoro-5-(Trimethylsilyl)Benzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure high purity and batch-to-batch consistency suitable for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.