Description

6H-Pyrrolo[3,4-B]Pyridine-6-Carboxylic Acid, Octahydro-, 1,1-Dimethylethyl Ester is a high-value, Boc-protected heterocyclic building block critical for advanced organic synthesis. This compound matters because it provides a protected nitrogen scaffold essential for constructing complex pharmaceutical intermediates with precise stereochemistry. It is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients. Its defined structure ensures reproducibility and quality in multi-step synthetic routes.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting neurological disorders and other therapeutic areas.
• Agrochemical Research: Used in the development of novel pesticides and herbicides, leveraging its fused bicyclic structure.
• Chemical Biology & Proteomics: Serves as a scaffold for designing molecular probes and enzyme inhibitors to study biological pathways.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological development and the exploration of new chemical spaces.
• Peptidomimetics: Acts as a constrained, non-natural amino acid analog in the design of peptide-like molecules with enhanced stability and bioavailability.

Basic Information

Product Name	6H-Pyrrolo[3,4-B]Pyridine-6-Carboxylic Acid, Octahydro-, 1,1-Dimethylethyl Ester
CAS No.	186203-81-6
Molecular Formula	C13H22N2O2
Molecular Weight	238.33 g/mol
Synonyms	tert-Butyl octahydro-6H-pyrrolo[3,4-b]pyridine-6-carboxylate; 1,1-Dimethylethyl Octahydro-6H-Pyrrolo[3,4-b]Pyridine-6-Carboxylate; Boc-Octahydro-6H-Pyrrolo[3,4-b]pyridine; (3aR,6aR)-1-Boc-octahydropyrrolo[3,4-b]pyrrole; (3aR,6aR)-tert-Butyl hexahydro-1H-pyrrolo[3,4-b]pyrrole-1-carboxylate; Octahydro-6H-pyrrolo[3,4-b]pyridine-6-carboxylic acid tert-butyl ester; BOC-Protected Octahydropyrrolopyridine
EINECS	Contact for details

Quality Control

Our 6H-Pyrrolo[3,4-B]Pyridine-6-Carboxylic Acid, Octahydro-, 1,1-Dimethylethyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) detailing purity, chiral purity (where applicable), and impurity profiles are available upon request to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if specified. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (if applicable)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.