Description

1-(Piperidin-4-Yl)-1H-Imidazo[4,5-C]Pyridin-2(3H)-One is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is of significant commercial interest for its role as a key building block in the synthesis of novel therapeutic agents. It is primarily required by research institutions and pharmaceutical companies engaged in drug discovery and development, particularly for projects targeting kinase inhibition and other critical biological pathways.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of active pharmaceutical ingredients (APIs) for investigational new drugs.
• Kinase Inhibitor Research: Serves as a core scaffold for developing potent and selective kinase inhibitors, a major class of oncology and anti-inflammatory therapeutics.
• Medicinal Chemistry: Used in structure-activity relationship (SAR) studies and lead optimization campaigns to improve drug candidate efficacy and safety profiles.
• Biochemical Tool Compound: Employed in vitro and in vivo to study specific enzyme functions and disease mechanisms.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis and scale-up projects under cGMP conditions.

Basic Information

Product Name	1-(Piperidin-4-Yl)-1H-Imidazo[4,5-C]Pyridin-2(3H)-One
CAS No.	185962-07-6
Molecular Formula	C11H14N4O
Molecular Weight	218.26 g/mol
Synonyms	1-(4-Piperidinyl)-1H-imidazo[4,5-c]pyridin-2(3H)-one; 1H-Imidazo[4,5-c]pyridin-2(3H)-one, 1-(4-piperidinyl)-; 1-(Piperidin-4-yl)-1,3-dihydro-2H-imidazo[4,5-c]pyridin-2-one; UNII-4Q5X2H1Q1I; 4Q5X2H1Q1I; 185962-07-6; 1-(Piperidin-4-yl)-1H-imidazo[4,5-c]pyridin-2-ol (tautomer)
EINECS	Contact for details

Quality Control

Our 1-(Piperidin-4-Yl)-1H-Imidazo[4,5-C]Pyridin-2(3H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the exacting standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). For long-term storage, consider under an inert atmosphere to maximize stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.