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Spirocyclohexane-1,2-1,3Dioxino4,5,6-Hiindolizine, 9-Azido-8-(1,1-Dimethylethyl)Dimethylsilyloxyoctahydro-, (3As,8S,9S,9Ar,9Br)- CAS NO 185899-34-7


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CAS No.:185899-34-7

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Spirocyclohexane-1,2-1,3Dioxino4,5,6-Hiindolizine, 9-Azido-8-(1,1-Dimethylethyl)Dimethylsilyloxyoctahydro-, (3As,8S,9S,9Ar,9Br)- is a complex, high-purity spirocyclic organic compound featuring both azido and silyl ether functional groups. This unique molecular architecture makes it a valuable advanced intermediate for the synthesis of novel pharmacologically active molecules and functional materials. It is primarily sought after by pharmaceutical R&D teams and specialty chemical manufacturers engaged in cutting-edge discovery programs.

Application

  • Pharmaceutical Intermediate: A key building block for the synthesis of complex heterocyclic drug candidates, particularly in oncology and CNS therapeutic areas.
  • Chemical Biology Probe Development: The azide group enables click chemistry (e.g., CuAAC) for bioconjugation and target identification studies.
  • Material Science Research: Used in the development of novel organic frameworks or polymers with specific optical or electronic properties.
  • Agrochemical Synthesis: Serves as a precursor for creating new active ingredients with spirocyclic motifs for crop protection.
  • Academic & Industrial Research: A versatile scaffold for methodological studies in organic synthesis and catalysis.

Basic Information

Product Name Spirocyclohexane-1,2-1,3Dioxino4,5,6-Hiindolizine, 9-Azido-8-(1,1-Dimethylethyl)Dimethylsilyloxyoctahydro-, (3As,8S,9S,9Ar,9Br)-
CAS No. 185899-34-7
Molecular Formula Contact for details
Molecular Weight Contact for details
Synonyms 9-Azido-8-((tert-butyldimethylsilyl)oxy)octahydrospiro[cyclohexane-1,2'-[1,3]dioxino[4,5,6-hi]indolizine]; (3aS,8S,9S,9aR,9bR)-9-Azido-8-((tert-butyldimethylsilyl)oxy)octahydrospiro[cyclohexane-1,2'-[1,3]dioxino[4,5,6-hi]indolizine]; 185899-34-7; TBDMS-protected azido spirocyclic intermediate; Azido-TBDMS-oxa-spiroindolizine
EINECS Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality protocols to ensure batch-to-batch consistency and high purity. Each lot is characterized using advanced analytical techniques including NMR, HPLC, and MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your R&D and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive; prolonged exposure should be avoided. Keep container tightly sealed under an inert atmosphere if long-term storage is required.

Specification

Item Specification
Appearance White to off-white solid
Identification (IR) Conforms to structure
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 95%
Water Content ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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