Description

(1S,2S)-N,N'-Diboc-1,2-Cyclohexanediamine is a high-purity, enantiomerically pure chiral diamine derivative, extensively utilized as a sophisticated building block in asymmetric synthesis. Its core value lies in providing a rigid, stereodefined scaffold for constructing complex molecular architectures, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries who require high-fidelity chiral intermediates.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for drugs targeting neurological and cardiovascular diseases.
• Ligand Synthesis: Used to prepare chiral ligands for asymmetric catalysis, including hydrogenation and C-C bond-forming reactions.
• Peptidomimetics & Macrocyclic Compounds: Serves as a constrained diamine unit in the design of peptide mimics and macrocyclic drug candidates.
• Polymer Chemistry: Acts as a monomer or chain extender for creating specialty polymers with specific chiral or rigid properties.
• Agrochemical Synthesis: Employed in the development of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Chemical Biology Probes: Useful for constructing molecular probes and tools to study biological systems and enzyme mechanisms.

Basic Information

Product Name	(1S,2S)-N,N'-Diboc-1,2-Cyclohexanediamine
CAS No.	185854-61-9
Molecular Formula	C₁₈H₃₄N₂O₄
Molecular Weight	342.48 g/mol
Synonyms	(1S,2S)-1,2-Bis[(tert-butoxycarbonyl)amino]cyclohexane; (1S,2S)-1,2-Diaminocyclohexane N,N'-di-Boc; (1S,2S)-N,N'-Di-Boc-1,2-diaminocyclohexane; (1S,2S)-Cyclohexane-1,2-diamine, N,N'-bis[(1,1-dimethylethoxy)carbonyl]-; (1S,2S)-1,2-Diaminocyclohexane di-Boc derivative; (1S,2S)-DACH-Boc₂; (1S,2S)-Boc-DACH-Boc; (1S,2S)-trans-N,N'-Di-Boc-1,2-diaminocyclohexane
EINECS	Contact for details

Quality Control

Our (1S,2S)-N,N'-Diboc-1,2-Cyclohexanediamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with high-grade chemical standards. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided to guarantee reliable and consistent performance in your critical synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under anhydrous conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.