Description

Indeno1,2-E1,3,4Oxadiazine-4A(3H)-Carboxylic Acid, 7-Chloro-2,5-Dihydro-2-(Methoxycarbonyl)4-(Trifluoromethoxy)Phenylaminocarbonyl-, Methyl Ester, (4Ar)- is a sophisticated, high-purity chemical intermediate designed for advanced synthesis. This compound matters because it provides a critical, structurally complex building block for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily needed by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries who require reliable, high-quality intermediates for their cutting-edge synthesis programs.

Application

• Pharmaceutical Intermediate: A key chiral building block in the research and synthesis of new drug candidates, particularly in central nervous system (CNS) and anti-infective therapeutic areas.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, leveraging its complex heterocyclic structure for novel modes of action.
• Chemical Research: Serves as a valuable scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Process Development: Employed in route scouting and optimization for the scalable production of target molecules in pilot plants and commercial manufacturing.
• Advanced Material Precursor: Potential use in the synthesis of specialized organic materials for electronic or optical applications.

Basic Information

Product Name	Indeno1,2-E1,3,4Oxadiazine-4A(3H)-Carboxylic Acid, 7-Chloro-2,5-Dihydro-2-(Methoxycarbonyl)4-(Trifluoromethoxy)Phenylaminocarbonyl-, Methyl Ester, (4Ar)-
CAS No.	185608-75-7
Molecular Formula	C22H17ClF3N3O6
Molecular Weight	511.84 g/mol
Synonyms	Methyl (4aR)-7-chloro-2,5-dihydro-2-[(methoxycarbonyl){[4-(trifluoromethoxy)phenyl]carbamoyl}amino]indeno[1,2-e][1,3,4]oxadiazine-4a(3H)-carboxylate; (4aR)-7-Chloro-2,5-dihydro-2-[(methoxycarbonyl){[4-(trifluoromethoxy)phenyl]carbamoyl}amino]indeno[1,2-e][1,3,4]oxadiazine-4a(3H)-carboxylic acid methyl ester; 185608-75-7; Indeno-oxadiazine carboxylate derivative; Chiral indeno-oxadiazine intermediate.
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems, ensuring batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical characterization, including HPLC for purity and chiral purity, NMR for structural confirmation, and mass spectrometry. A detailed Certificate of Analysis (COA) documenting identity, purity, and impurity profiles is provided with every shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if specified. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.