Description

3H-Oxazolo[3,4-A]Pyridin-3-One, 1-Ethenylhexahydro-6,7,8-Trihydroxy-, (1S,6S,7R,8R,8As)- (9Ci) is a high-purity, stereochemically defined heterocyclic compound of significant interest in advanced organic synthesis. This complex molecule serves as a critical chiral building block or synthetic intermediate for the development of novel active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily needed by pharmaceutical R&D teams, process chemists, and specialty chemical manufacturers engaged in creating complex molecular architectures with precise stereochemical control.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the multi-step synthesis of complex drug candidates, particularly in therapeutic areas requiring high stereochemical purity.
• Asymmetric Synthesis: Utilized as a sophisticated scaffold or reagent in catalytic and stoichiometric asymmetric transformations to introduce multiple stereocenters.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and library synthesis for novel bioactive compound discovery.
• Fine Chemical Production: Serves as a high-value intermediate in the manufacture of specialty chemicals, agrochemicals, or advanced materials.
• Academic & Industrial R&D: Used in methodological development and chemical biology research exploring new heterocyclic chemistry and glycosidase-related mechanisms.

Basic Information

Item	Detail
Product Name	3H-Oxazolo[3,4-A]Pyridin-3-One, 1-Ethenylhexahydro-6,7,8-Trihydroxy-, (1S,6S,7R,8R,8As)- (9Ci)
CAS No.	185533-43-1
Molecular Formula	C10H15NO5
Molecular Weight	229.23 g/mol
Synonyms	1-Vinylhexahydro-6,7,8-trihydroxy-3H-oxazolo[3,4-a]pyridin-3-one; (1S,6S,7R,8R,8aR)-1-Ethenylhexahydro-6,7,8-trihydroxy-3H-oxazolo[3,4-a]pyridin-3-one; 1,6,7,8-Tetradeoxy-1-vinylnojirimycin; Dihydroxyvinylazepane; Oxazolopyridinone derivative; Chiral oxazolo-pyridinone; CAS 185533-43-1
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems, ensuring batch-to-batch consistency and high chemical purity. Quality is verified through comprehensive analytical techniques including HPLC, chiral analysis, NMR, and mass spectrometry to confirm identity, stereochemical purity, and impurity profiles. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all critical specifications. We support development and commercial projects requiring material that meets GMP-grade standards for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions when necessary to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.