Description

2-Chloro-3-Hydroxyisonicotinic Acid is a high-purity, multi-functional heterocyclic building block essential for advanced organic synthesis. This compound matters because it serves as a critical precursor for developing novel active pharmaceutical ingredients (APIs) and agrochemicals, offering a unique halogenated and hydroxylated pyridine scaffold. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Development: Used as a building block for creating new herbicides, fungicides, and plant growth regulators.
• Ligand Synthesis: Serves as a precursor for chelating agents and metal-organic frameworks (MOFs) in material science.
• Chemical Research: Employed in academic and industrial R&D for exploring new heterocyclic chemistry and reaction pathways.
• Fine Chemical Production: Integrated into multi-step synthesis processes for high-value specialty chemicals.

Basic Information

Product Name	2-Chloro-3-Hydroxyisonicotinic Acid
CAS No.	185423-02-3
Molecular Formula	C6H4ClNO3
Molecular Weight	173.55 g/mol
Synonyms	3-Hydroxy-2-chloroisonicotinic acid; 2-Chloro-3-hydroxypyridine-4-carboxylic acid; 4-Pyridinecarboxylic acid, 2-chloro-3-hydroxy-; Isonicotinic acid, 2-chloro-3-hydroxy-; 2-Chloro-3-hydroxy-4-pyridinecarboxylic acid; 2-Chloro-3-hydroxypicolinic acid
EINECS	Contact for details

Quality Control

Our 2-Chloro-3-Hydroxyisonicotinic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and should be handled under inert atmosphere for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.