Description

2-Pyridinepropanoicacid,-α--Amino-5-Hydroxy-,(R)-(9Ci) is a chiral, non-proteinogenic amino acid derivative featuring a pyridine ring, making it a valuable synthetic intermediate and building block. This compound matters for its role in the research and development of novel pharmaceuticals, particularly in the synthesis of complex molecules with specific stereochemistry. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for creating active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Key chiral building block for the synthesis of potential active pharmaceutical ingredients (APIs), especially those targeting neurological or metabolic pathways.
• Agrochemical Research: Used in developing novel herbicides, fungicides, or plant growth regulators that require specific stereochemical configurations for efficacy.
• Ligand Synthesis: Serves as a precursor for creating chiral ligands used in asymmetric catalysis to produce enantiomerically pure compounds.
• Peptidomimetics: Incorporated into the design of peptide analogs and mimetics for drug discovery programs, leveraging its unique pyridine-containing structure.
• Biochemical Research: Utilized as a substrate or inhibitor in enzymatic studies due to its structural similarity to natural amino acids.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis for creating complex, high-value specialty chemicals.

Basic Information

Item	Detail
Product Name	2-Pyridinepropanoicacid,-α--Amino-5-Hydroxy-,(R)-(9Ci)
CAS No.	185389-91-7
Molecular Formula	C8H10N2O3
Molecular Weight	182.18 g/mol
Synonyms	(R)-2-Amino-3-(5-hydroxypyridin-2-yl)propanoic acid; (R)-2-Amino-3-(5-hydroxy-2-pyridyl)propionic acid; (R)-α-Amino-5-hydroxy-2-pyridinepropanoic acid; (R)-2-Amino-3-(5-hydroxypyridin-2-yl)propanoic acid; (R)-5-Hydroxypyridylalanine; (R)-2-Pyridinealanine, 5-hydroxy-; (R)-HPA; (9CI) designation for CAS indexing.
EINECS	Contact for details

Quality Control

Our 2-Pyridinepropanoicacid,-α--Amino-5-Hydroxy-,(R)-(9Ci) is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with exacting standards for research and development use. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture uptake, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.