Description

1-(2,6-Dichloropyridin-4-Yl)Ethanone is a high-purity, versatile chlorinated pyridine derivative that serves as a critical building block in advanced organic synthesis. Its value lies in its unique substitution pattern, which makes it an essential intermediate for constructing complex molecules in pharmaceutical and agrochemical research. This compound is primarily needed by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), crop protection agents, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) and anti-infective agents.
• Agrochemical Synthesis: Building block for developing advanced herbicides, insecticides, and fungicides, leveraging the bioactivity of the dichloropyridine moiety.
• Ligand and Catalyst Development: Used to create specialized pyridine-based ligands for transition metal catalysis and organometallic chemistry.
• Material Science Research: Intermediate for synthesizing functionalized polymers and organic electronic materials requiring specific halogenated aromatic units.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for use in custom synthesis projects and scale-up campaigns.

Basic Information

Product Name	1-(2,6-Dichloropyridin-4-Yl)Ethanone
CAS No.	185319-20-4
Molecular Formula	C7H5Cl2NO
Molecular Weight	190.03 g/mol
Synonyms	2',6'-Dichloro-4'-acetylpyridine; 4-Acetyl-2,6-dichloropyridine; 2,6-Dichloro-4-acetylpyridine; 1-(2,6-Dichloro-4-pyridinyl)ethanone; Ethanone, 1-(2,6-dichloro-4-pyridinyl)-; 4-Pyridinecarbonyl chloride, 2,6-dichloro- (related); 1-(2,6-Dichloropyridin-4-yl)ethan-1-one
EINECS	Contact for details

Quality Control

Our 1-(2,6-Dichloropyridin-4-Yl)Ethanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most critical synthesis steps.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in its original packaging to minimize exposure to moisture and atmospheric contaminants. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.