Description

2-(5-Chloropyridin-2-Yl)Acetonitrile is a versatile pyridine-based nitrile building block, essential for advanced organic synthesis and pharmaceutical research. Its molecular structure, featuring both a chloropyridine ring and a reactive nitrile group, makes it a critical intermediate for constructing complex heterocyclic compounds. This high-purity intermediate is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and antiviral drug candidates.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides, fungicides, and insecticides, leveraging the bioactivity of the chloropyridine moiety.
• Ligand and Catalyst Development: Serves as a precursor for creating novel nitrogen-containing ligands used in homogeneous catalysis and material science.
• Functional Material Research: Employed in the synthesis of organic electronic materials, dyes, and photoactive compounds.
• Custom Synthesis and Contract Manufacturing: A fundamental building block for custom chemical synthesis services targeting novel molecular entities.

Basic Information

Product Name	2-(5-Chloropyridin-2-Yl)Acetonitrile
CAS No.	185315-51-9
Molecular Formula	C7H5ClN2
Molecular Weight	152.58 g/mol
Synonyms	2-(5-Chloro-2-pyridinyl)acetonitrile; (5-Chloropyridin-2-yl)acetonitrile; 5-Chloro-2-pyridineacetonitrile; 2-Cyanoethyl-5-chloropyridine; 5-Chloro-2-(cyanomethyl)pyridine; α-Cyano-5-chloro-2-picoline; 185315-51-9
EINECS	Contact for details

Quality Control

Our 2-(5-Chloropyridin-2-Yl)Acetonitrile is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with each shipment, confirming compliance with customer specifications and internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.