Description

Methyl 4-(((9H-Fluoren-9-Yl)Methoxy)Carbonylamino)Pyrrolidine-2-Carboxylate is a high-purity, protected amino acid derivative essential for advanced organic synthesis. This compound matters as a critical building block in solid-phase peptide synthesis (SPPS), enabling the controlled assembly of complex peptides and peptidomimetics. Pharmaceutical R&D and biotechnology companies need it for developing novel therapeutic agents, including peptide-based drugs and diagnostic probes.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key Fmoc-protected proline derivative for the automated, sequential construction of peptides.
• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of active pharmaceutical ingredients (APIs) for peptide therapeutics.
• Bioconjugation & Probe Development: Used to incorporate proline analogs into fluorescent or affinity tags for biological studies.
• Combinatorial Chemistry: A valuable scaffold in libraries for high-throughput screening to discover new bioactive compounds.
• Academic & Industrial Research: Fundamental reagent for exploring peptide structure-activity relationships and novel synthetic methodologies.

Basic Information

Product Name	Methyl 4-(((9H-Fluoren-9-Yl)Methoxy)Carbonylamino)Pyrrolidine-2-Carboxylate
CAS No.	185304-44-3
Molecular Formula	C22H22N2O5
Molecular Weight	394.42 g/mol
Synonyms	Fmoc-Pro-OMe; Fmoc-L-Proline methyl ester; (S)-1-((((9H-Fluoren-9-yl)methoxy)carbonyl)pyrrolidine-2-carboxylic acid methyl ester; Methyl (S)-1-(((9H-fluoren-9-yl)methoxy)carbonyl)pyrrolidine-2-carboxylate; Methyl N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-prolinate; Fmoc-Proline methyl ester; N-α-Fmoc-L-proline methyl ester; Methyl N-Fmoc-L-prolinate
EINECS	Contact for details

Quality Control

Our Methyl 4-(((9H-Fluoren-9-Yl)Methoxy)Carbonylamino)Pyrrolidine-2-Carboxylate is manufactured under strict quality systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral analysis, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) with detailed specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.