Description

3-(2-Fluoro-Phenyl)-3-Oxo-Propionic Acid Methyl Ester is a high-purity fluorinated aromatic keto ester, serving as a critical advanced intermediate in modern organic synthesis. Its value lies in providing a versatile molecular scaffold for constructing complex pharmacophores and functional materials. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce fluorinated motifs into target molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and fungicides, where the fluorine atom enhances biological activity and environmental stability.
• Material Science Precursor: Serves as a monomer or cross-linking agent in the production of specialty polymers and liquid crystals with tailored optical or electronic properties.
• Chemical Research & Development: A versatile reagent for exploring new fluorination methodologies and constructing β-keto ester derivatives in academic and industrial R&D labs.
• Fluorine Chemistry: Fundamental substrate for studying structure-activity relationships (SAR) and for introducing the 2-fluorophenyl group into more complex molecular architectures.

Basic Information

Product Name	3-(2-Fluoro-Phenyl)-3-Oxo-Propionic Acid Methyl Ester
CAS No.	185302-86-7
Molecular Formula	C10H9FO3
Molecular Weight	196.18 g/mol
Synonyms	Methyl 3-(2-fluorophenyl)-3-oxopropanoate; Methyl 2-fluoro-β-oxobenzenepropanoate; 3-Oxo-3-(2-fluorophenyl)propionic acid methyl ester; 2-Fluoro-β-ketobenzenepropanoic acid methyl ester; Methyl (2-fluorobenzoyl)acetate; 3-(2-Fluorophenyl)-3-oxopropanoic acid methyl ester; 185302-86-7; Methyl 3-oxo-3-(2-fluorophenyl)propanoate
EINECS	Contact for details

Quality Control

Our production of 3-(2-Fluoro-Phenyl)-3-Oxo-Propionic Acid Methyl Ester adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced chromatographic and spectroscopic techniques (HPLC, GC, NMR, IR) against established internal specifications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed when not in use to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.