Description

2(3H)-Furanone, 4-Ethynyldihydro-3,5-Dimethyl-, [3S-(3Alpha,4Beta,5Beta)]- (9Ci) is a high-value, stereochemically defined furanone derivative featuring an ethynyl functional group. This compound serves as a sophisticated chiral building block and key synthetic intermediate in advanced organic synthesis, enabling the construction of complex molecular architectures. It is primarily utilized by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the research and synthesis of novel drug candidates, particularly in areas requiring specific stereochemistry.
• Agrochemical Research: Used in the development of new pesticides, herbicides, and plant growth regulators where the furanone core and ethynyl group impart unique biological activity.
• Organic Synthesis Building Block: Employed in complex organic transformations, including cycloadditions and cross-coupling reactions, to introduce functionalized furanone motifs.
• Material Science Precursor: Acts as a monomer or precursor for synthesizing specialized polymers and advanced organic materials with tailored properties.
• Academic & Industrial R&D: A valuable reagent for methodological studies in synthetic organic chemistry and catalysis within university and corporate research laboratories.

Basic Information

Product Name	2(3H)-Furanone, 4-Ethynyldihydro-3,5-Dimethyl-, [3S-(3Alpha,4Beta,5Beta)]- (9Ci)
CAS No.	185246-59-7
Molecular Formula	C9H10O2
Molecular Weight	150.17 g/mol
Synonyms	(3S,4R,5R)-4-Ethynyl-3,5-dimethyl-4,5-dihydrofuran-2(3H)-one; (3S,4R,5R)-4-Ethynyl-3,5-dimethyldihydro-2(3H)-furanone; 4-Ethynyldihydro-3,5-dimethyl-2(3H)-furanone, (3S,4R,5R)-; [3S-(3α,4β,5β)]-4-Ethynyldihydro-3,5-dimethyl-2(3H)-furanone; Chiral 4-Ethynyl Dihydrofuranone; 4-Ethynyl-3,5-dimethyldihydrofuran-2(3H)-one (stereoisomer)
EINECS	Contact for details

Quality Control

Our production of 2(3H)-Furanone, 4-Ethynyldihydro-3,5-Dimethyl-, [3S-(3Alpha,4Beta,5Beta)]- (9Ci) adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity analysis, to ensure high chemical and stereochemical purity suitable for demanding R&D and scale-up applications. Certificates of Analysis (COA) with detailed chromatographic data (HPLC, GC) are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.