Description

Ferroquine is a synthetic organometallic compound belonging to the class of ferroquines, which are antimalarial agents. This compound is of significant interest in pharmaceutical research and development due to its unique mechanism of action against drug-resistant strains of *Plasmodium falciparum*. It is primarily utilized by research institutions, pharmaceutical companies, and contract development and manufacturing organizations (CDMOs) engaged in the discovery and synthesis of novel antimalarial therapeutics.

Application

• Pharmaceutical Research & Development: As a key intermediate or active pharmaceutical ingredient (API) in the development of new antimalarial drugs.
• Mechanistic Studies: For investigating the biological activity and resistance mechanisms of ferroquine-based therapies in parasitology.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method validation in laboratories.
• Preclinical Studies: Used in *in vitro* and *in vivo* studies to evaluate efficacy, pharmacokinetics, and toxicity profiles.
• Chemical Synthesis: As a building block for the synthesis of related ferroquine derivatives and analogs with potential enhanced properties.

Basic Information

Product Name	Ferroquine
CAS No.	185055-67-8
Molecular Formula	C₂₀H₂₄FeN₂
Molecular Weight	348.27 g/mol
Synonyms	SR97193; Ferroquine (SR 97193); 7-Chloro-4-[[(2-[(dimethylamino)methyl]phenyl)(ferrocen-1-yl)amino]methyl]quinoline; 1-[[7-Chloro-4-quinolyl]methyl]-N-[(2-[(dimethylamino)methyl]phenyl)]-N-(ferrocen-1-yl)amine; Ferroquine base
EINECS	Contact for details

Quality Control

Our Ferroquine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification by spectroscopic methods (IR, NMR), purity determination by HPLC, and control of specified impurities. A detailed Certificate of Analysis (COA) is provided with each shipment, ensuring traceability and compliance with your research-grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. This material is light-sensitive and easily oxidized; prolonged exposure to air and light should be avoided to maintain stability.

Specification

Item	Specification
Appearance	Orange to red solid
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5% Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.