Description

2-Chloro-4-Iodo-Nicotinic Acid Methyl Ester is a halogenated nicotinic acid derivative that serves as a critical synthetic intermediate in advanced organic chemistry. This compound is valued for its unique reactivity profile, enabling the construction of complex heterocyclic scaffolds. It is primarily utilized by research institutions and pharmaceutical development companies engaged in the synthesis of novel active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of complex drug candidates, particularly in medicinal chemistry research.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides due to its halogenated pyridine structure.
• Chemical Synthesis: Serves as a versatile precursor for further functionalization via cross-coupling reactions (e.g., Suzuki, Stille) or nucleophilic substitution.
• Material Science: Potential intermediate in the creation of specialty chemicals and functional materials.
• Academic & R&D: Employed in university and corporate laboratories for methodological studies and novel compound library generation.

Basic Information

Product Name	2-Chloro-4-Iodo-Nicotinic Acid Methyl Ester
CAS No.	185041-05-8
Molecular Formula	C7H5ClINO2
Molecular Weight	297.48 g/mol
Synonyms	Methyl 2-Chloro-4-iodonicotinate; 2-Chloro-4-iodo-3-pyridinecarboxylic acid methyl ester; 3-Pyridinecarboxylic acid, 2-chloro-4-iodo-, methyl ester; Methyl 2-chloro-4-iodopyridine-3-carboxylate; 2-Chloro-4-iodonicotinic acid methyl ester; 185041-05-8; Methyl 2-chloro-4-iodo-3-pyridinecarboxylate
EINECS	Contact for details

Quality Control

Our 2-Chloro-4-Iodo-Nicotinic Acid Methyl Ester is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee it meets the rigorous standards required for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling should be minimized under direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.