Description

(4-Bromo-2,6-Difluorophenyl)Trimethylsilane is a high-value organosilicon intermediate featuring a halogenated aromatic ring system. This compound is critical for its role as a versatile building block in advanced organic synthesis, particularly in cross-coupling reactions. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries who require precise functionalization of complex molecules.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds requiring halogenated aryl motifs.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the difluorophenyl group imparts specific biological activity and stability.
• Material Science Research: Acts as a monomer or functionalization agent in the creation of specialty polymers, liquid crystals, and advanced organic electronic materials.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and Negishi couplings due to the presence of the bromine atom, enabling the formation of new carbon-carbon bonds.
• Ligand and Catalyst Development: Utilized in the preparation of sophisticated ligands for transition metal catalysis and organometallic complexes.
• Chemical Research & Development: A valuable tool for medicinal chemistry and process chemistry in exploring new synthetic pathways and molecular architectures.

Basic Information

Product Name	(4-Bromo-2,6-Difluorophenyl)Trimethylsilane
CAS No.	184910-20-1
Molecular Formula	C9H11BrF2Si
Molecular Weight	265.17 g/mol
Synonyms	1-Bromo-3,5-difluoro-4-(trimethylsilyl)benzene; Trimethyl(4-bromo-2,6-difluorophenyl)silane; 4-Bromo-2,6-difluorophenyltrimethylsilane; (4-Bromo-2,6-difluorophenyl)trimethylsilicon; Benzene, 1-bromo-3,5-difluoro-4-(trimethylsilyl)-; Silane, trimethyl(4-bromo-2,6-difluorophenyl)-
EINECS	Contact for details

Quality Control

Our (4-Bromo-2,6-Difluorophenyl)Trimethylsilane is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.