Description

(R)-2,3-Dihydroxy-3-Methyl-Butyric Acid Benzyl Ester is a high-value chiral building block and intermediate of significant importance in asymmetric synthesis. Its defined stereochemistry and functional groups make it a critical precursor for the development of complex, biologically active molecules. This compound is essential for research and production in the pharmaceutical and fine chemical industries, particularly for synthesizing active pharmaceutical ingredients (APIs) and advanced materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of complex drug molecules, including antiviral agents, enzyme inhibitors, and other bioactive compounds.
• Asymmetric Synthesis: Used as a starting material or auxiliary in stereoselective reactions to construct molecules with high enantiomeric purity.
• Fine Chemical Production: Serves as a building block for creating specialty chemicals, flavors, fragrances, and advanced polymers.
• Academic & Industrial Research: A valuable reagent in medicinal chemistry and process development for exploring new synthetic pathways.
• Catalyst and Ligand Development: Can be utilized in the preparation of chiral catalysts or ligands for catalytic asymmetric transformations.

Basic Information

Product Name	(R)-2,3-Dihydroxy-3-Methyl-Butyric Acid Benzyl Ester
CAS No.	184528-76-5
Molecular Formula	C12H16O4
Molecular Weight	224.25 g/mol
Synonyms	(R)-Benzyl 2,3-Dihydroxy-3-methylbutanoate; (R)-Benzyl 2,3-Dihydroxy-3-methylbutyrate; (R)-2,3-Dihydroxy-3-methylbutyric Acid Benzyl Ester; (R)-3-Methyl-2,3-dihydroxybutyric Acid Benzyl Ester; (R)-α,β-Dihydroxy-β-methylbutyric Acid Benzyl Ester; (R)-HMB Benzyl Ester; Benzyl (R)-2,3-Dihydroxy-3-methylbutanoate
EINECS	Contact for details

Quality Control

Our production of (R)-2,3-Dihydroxy-3-Methyl-Butyric Acid Benzyl Ester adheres to stringent quality management protocols to ensure batch-to-batch consistency and high chemical purity. Each lot is characterized by advanced analytical techniques, including chiral HPLC, to confirm identity, enantiomeric excess (ee), and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. For long-term storage under inert atmosphere, please contact us for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.