Description

L-Homoserine, o-Amino-, Ethyl Ester (9Ci) is a protected derivative of the non-proteinogenic amino acid homoserine, specifically designed for advanced organic synthesis and pharmaceutical research. This high-purity building block is critical for the controlled synthesis of complex peptides, heterocyclic compounds, and other bioactive molecules where precise stereochemistry and functional group manipulation are required. It serves as a key intermediate for researchers and manufacturers in pharmaceutical development, agrochemical research, and specialty chemical production who require reliable, high-quality chiral synthons.

Application

• Pharmaceutical Intermediate: A crucial chiral building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in the development of enzyme inhibitors and receptor modulators.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis to incorporate modified homoserine residues into peptide chains for structure-activity relationship (SAR) studies.
• Agrochemical Research: Serves as a precursor in the development of new herbicides, fungicides, and plant growth regulators with specific chiral activity.
• Biochemical Research: Employed in metabolic pathway studies and as a substrate or inhibitor for enzymes involved in amino acid metabolism.
• Specialty Chemical Production: Acts as a starting material for the manufacture of fine chemicals, liquid crystals, and advanced polymeric materials.

Basic Information

Product Name	L-Homoserine, o-Amino-, Ethyl Ester (9Ci)
CAS No.	184245-39-4
Molecular Formula	C7H14N2O3
Molecular Weight	174.20 g/mol
Synonyms	L-2-Amino-4-(ethoxycarbonyl)butanoic acid; (2S)-2-Amino-4-(ethoxycarbonyl)butanoic acid; Ethyl L-2-amino-4-carboxybutanoate; L-2-Amino-4-carboxybutyric acid ethyl ester; L-Homoserine ethyl ester; L-2-Amino-4-(ethoxycarbonyl)butyric acid; L-α-Amino-γ-carbethoxybutyric acid; L-2-Amino-4-(ethoxyoxoethyl)butanoic acid
EINECS	Contact for details

Quality Control

Our L-Homoserine, o-Amino-, Ethyl Ester (9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting identity, purity, and specific impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.