Description

1,3-Dioxaspiro[4.4]Nonan-2-One, 4-Methyl-, (-)- is a chiral spirocyclic acetal derivative, a versatile and valuable building block in advanced organic synthesis. Its unique spirocyclic structure and defined stereochemistry make it a critical intermediate for constructing complex molecular architectures with high precision. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries, particularly for developing active pharmaceutical ingredients (APIs), chiral ligands, and specialty materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and antiviral research.
• Asymmetric Catalysis: Used in the preparation of chiral ligands and catalysts for enantioselective synthesis.
• Fine Chemical Synthesis: Serves as a building block for fragrances, agrochemicals, and other high-value specialty chemicals.
• Material Science Research: Employed in the development of polymers and advanced organic materials with specific stereochemical properties.
• Academic & R&D: A valuable reagent for methodological studies in organic chemistry and total synthesis of natural products.

Basic Information

Product Name	1,3-Dioxaspiro[4.4]Nonan-2-One, 4-Methyl-, (-)-
CAS No.	184007-14-5
Molecular Formula	C9H14O3
Molecular Weight	170.21 g/mol
Synonyms	(-)-4-Methyl-1,3-dioxaspiro[4.4]nonan-2-one; (4S)-4-Methyl-1,3-dioxaspiro[4.4]nonan-2-one; (S)-4-Methyl-1,3-dioxaspiro[4.4]nonan-2-one; 4-Methyl-1,3-dioxaspiro[4.4]nonan-2-one, (-)-; Spirocyclic acetal ketone; Chiral spiro acetal
EINECS	Contact for details

Quality Control

Our production of 1,3-Dioxaspiro[4.4]Nonan-2-One, 4-Methyl-, (-)- adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is characterized using advanced analytical techniques including chiral HPLC, GC, NMR, and IR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profile is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed when not in use to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.