Description

α-D-Mannopyranose, 2,3,4,6-Tetrabenzoate 1-(2,2,2-Trichloroethanimidate) is a sophisticated glycosyl donor intermediate, pivotal for the stereoselective construction of complex carbohydrate structures. Its core value lies in enabling precise glycosylation reactions in synthetic organic chemistry, particularly for the assembly of oligosaccharides and glycoconjugates. This high-purity building block is essential for researchers and process chemists in pharmaceutical development, glycobiology research, and the synthesis of bioactive natural products.

Application

• Glycosylation Reagent: A key donor for the stereoselective synthesis of α-mannosidic linkages in oligosaccharides and glycoconjugates.
• Pharmaceutical Intermediate: Used in the research and development of novel carbohydrate-based therapeutics, including antibiotics and antiviral agents.
• Glycobiology Probe Synthesis: Enables the creation of labeled or modified mannose-containing compounds for studying biological recognition processes.
• Complex Carbohydrate Synthesis: Critical for constructing defined segments of bacterial cell wall polysaccharides or plant-derived glycans.
• Process Chemistry: Serves as a reliable, high-purity starting material for scaling up the production of carbohydrate-active pharmaceutical ingredients (APIs).
• Academic & Industrial R&D: A fundamental tool in synthetic chemistry laboratories for methodology development and target molecule synthesis.

Basic Information

Product Name	α-D-Mannopyranose, 2,3,4,6-Tetrabenzoate 1-(2,2,2-Trichloroethanimidate)
CAS No.	183901-63-5
Molecular Formula	C35H28Cl3NO9
Molecular Weight	713.95 g/mol
Synonyms	1-O-(2,2,2-Trichloroethanimidoyl)-2,3,4,6-tetra-O-benzoyl-α-D-mannopyranose; 2,3,4,6-Tetra-O-benzoyl-α-D-mannopyranosyl Trichloroacetimidate; α-D-Mannopyranosyl Trichloroacetimidate, 2,3,4,6-Tetrabenzoate; Trichloroacetimidate Mannose Donor; Mannosyl Trichloroacetimidate (Tetrabenzoylated); Glycosyl Donor 183901-63-5; TCA Mannose Donor
EINECS	Contact for details

Quality Control

Every batch of our α-D-Mannopyranose, 2,3,4,6-Tetrabenzoate 1-(2,2,2-Trichloroethanimidate) is synthesized and purified under controlled conditions to ensure exceptional chemical purity and lot-to-lot consistency, critical for reproducible glycosylation outcomes. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with stringent R&D and process chemistry standards. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and reactivity. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Specific Rotation	Contact for details
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.