Description

5-Amino-2-Methoxy-Isonicotinic Acid is a high-purity, functionalized pyridine derivative serving as a critical building block in advanced organic synthesis. Its value lies in its bifunctional structure, featuring both an amino group and a carboxylic acid, which enables its use in constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, especially in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides, leveraging its heterocyclic core for bioactivity.
• Ligand and Catalyst Preparation: Serves as a precursor for chelating ligands in metal-catalyzed reactions and coordination chemistry.
• Material Science Research: Employed in the synthesis of functionalized polymers and organic electronic materials.
• Chemical Biology Probes: Utilized to create tagged molecules for studying biological pathways and protein interactions.
• Custom Synthesis and Contract Manufacturing: A versatile starting material for bespoke chemical synthesis services.

Basic Information

Product Name	5-Amino-2-Methoxy-Isonicotinic Acid
CAS No.	183741-91-5
Molecular Formula	C7H8N2O3
Molecular Weight	168.15 g/mol
Synonyms	2-Methoxy-5-aminoisonicotinic acid; 5-Amino-2-methoxypyridine-4-carboxylic acid; 4-Pyridinecarboxylic acid, 5-amino-2-methoxy-; Isonicotinic acid, 5-amino-2-methoxy-; AMIA; 183741-91-5; 5-Amino-2-methoxy-4-pyridinecarboxylic acid
EINECS	Contact for details

Quality Control

Every batch of 5-Amino-2-Methoxy-Isonicotinic Acid is produced under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment. We adhere to cGMP principles where applicable to support our clients in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed and away from direct light and moisture to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.