Description

Benzenepropanoic Acid, -Ba--Hydroxy--α-,4-Dimethyl-, Ethyl Ester, (R*,S*)- (9Ci) is a chiral ester derivative of a substituted benzenepropanoic acid, characterized by its specific stereochemistry. This compound is a valuable intermediate in advanced organic synthesis, particularly for the construction of complex molecules where precise stereocontrol is required. It is primarily sought by pharmaceutical and fine chemical research and development teams for applications in drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of active pharmaceutical ingredients (APIs), especially for candidates targeting neurological and metabolic disorders.
• Asymmetric Synthesis: Utilized as a precursor or auxiliary in catalytic asymmetric reactions to introduce stereogenic centers with high enantiomeric excess.
• Ligand and Catalyst Development: Serves as a scaffold for creating novel chiral ligands and organocatalysts used in enantioselective transformations.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, agrochemicals, and advanced materials requiring specific stereochemistry.
• Academic and Industrial R&D: Used in research laboratories for methodological studies and the development of new synthetic pathways.

Basic Information

Product Name	Benzenepropanoic Acid, -Ba--Hydroxy--α-,4-Dimethyl-, Ethyl Ester, (R*,S*)- (9Ci)
CAS No.	183613-19-6
Molecular Formula	C13H18O3
Molecular Weight	222.28 g/mol
Synonyms	Ethyl 2-hydroxy-2-(4-methylphenyl)butanoate; Ethyl 2-hydroxy-2-(p-tolyl)butanoate; α-Hydroxy-α-(4-methylbenzyl)-butyric acid ethyl ester; (R*,S*)-Ethyl 2-hydroxy-2-(4-methylphenyl)butanoate; Benzenepropanoic acid, α-hydroxy-α,4-dimethyl-, ethyl ester, (R*,S*)-; (RS)-Ethyl 2-hydroxy-2-(4-methylphenyl)butyrate; 2-Hydroxy-2-(4-methylphenyl)butanoic acid ethyl ester
EINECS	Contact for details

Quality Control

Our production of this chiral intermediate adheres to strict quality protocols to ensure batch-to-batch consistency and purity suitable for sensitive synthetic applications. Quality is verified through advanced analytical techniques including HPLC, GC, and chiral analysis. A comprehensive Certificate of Analysis (COA) detailing identity, purity (assay), enantiomeric/excess, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.