Description

5-Bromo-n-Methoxy-n-Methylnicotinamide is a high-purity, functionalized nicotinamide derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its unique halogenated and methoxy-substituted pyridine core, which enables precise molecular modifications in complex chemical architectures. It is primarily utilized by research institutions and pharmaceutical development teams engaged in the creation of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those targeting neurological and metabolic disorders.
• Agrochemical Research: Used in the development of new herbicides and pesticides, leveraging its halogenated heterocyclic structure.
• Ligand and Catalyst Development: Serves as a sophisticated ligand scaffold in transition metal catalysis for asymmetric synthesis.
• Material Science: Incorporated into the design of organic electronic materials and advanced polymers.
• Chemical Biology Probes: Utilized in the creation of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds under cGMP conditions.

Basic Information

Product Name	5-Bromo-n-Methoxy-n-Methylnicotinamide
CAS No.	183608-47-1
Molecular Formula	C9H11BrN2O2
Molecular Weight	259.10 g/mol
Synonyms	5-Bromo-N-methoxy-N-methylnicotinamide; 5-Bromo-N-methoxy-N-methyl-3-pyridinecarboxamide; 3-Pyridinecarboxamide, 5-bromo-N-methoxy-N-methyl-; 5-Bromo-3-(N-methoxy-N-methylcarbamoyl)pyridine; 5-Bromo-3-pyridinecarboxylic acid methoxy(methyl)amide; 5-Bromo-3-(methoxy(methyl)carbamoyl)pyridine; 5-Bromo-N-methoxy-N-methyl-3-pyridinecarboxamide; 5-Br-N-MeO-N-Me-nicotinamide
EINECS	Contact for details

Quality Control

Our 5-Bromo-n-Methoxy-n-Methylnicotinamide is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Production adheres to in-house specifications aligned with ICH guidelines for impurities. Every lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity (by HPLC), and impurity profiles. We support development and commercial projects with full traceability and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the original container tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.