Description

Carbamic Acid, (1-Formyl-3-Pentynyl)-, 1,1-Dimethylethyl Ester (9Ci) is a specialized organic building block featuring both a formyl and a terminal alkyne functional group, protected by a tert-butyl carbamate (Boc) moiety. This unique molecular architecture makes it a versatile and valuable intermediate for advanced synthetic chemistry, particularly in the construction of complex molecules. It is primarily utilized by pharmaceutical R&D and fine chemical synthesis teams for applications in medicinal chemistry and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry: Used in structure-activity relationship (SAR) studies and for introducing functionalized alkynyl segments into target molecules.
• Peptidomimetics & PROTACs: Serves as a precursor for constructing peptide-like structures and proteolysis-targeting chimeras (PROTACs).
• Click Chemistry: The terminal alkyne group enables participation in copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions for bioconjugation and material science.
• Organic Synthesis: Employed in multi-step synthetic routes to create heterocycles, natural product analogs, and other advanced organic compounds.
• Agrochemical Research: Acts as an intermediate in the development of new crop protection agents and herbicides.

Basic Information

Product Name	Carbamic Acid, (1-Formyl-3-Pentynyl)-, 1,1-Dimethylethyl Ester (9Ci)
CAS No.	183500-62-1
Molecular Formula	C11H17NO3
Molecular Weight	211.26 g/mol
Synonyms	tert-Butyl (1-formylpent-3-yn-1-yl)carbamate; N-Boc-3-butyn-1-alanine aldehyde; 1-((tert-Butoxycarbonyl)amino)-4-pentyn-1-al; (1-Formyl-3-pentynyl)carbamic acid tert-butyl ester; N-(tert-Butoxycarbonyl)-4-pentynal-1-amine; Boc-NH-CH(CHO)-CH2-C≡CH; 183500-62-1
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch is characterized using advanced analytical techniques to confirm identity, purity, and consistency. Certificates of Analysis (COA) detailing specific batch results are available upon request. We adhere to a quality management system suitable for supplying GMP-ready intermediates for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0% (Area %)
Water Content (KF)	≤ 0.5%
Solvent Residue (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.