Description

2-Bromo-4-Pyridine Acetic Acid is a versatile pyridine derivative and a key brominated building block in advanced organic synthesis. This compound is highly valued for its role in constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and functional materials. It is primarily sought after by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for its utility in cross-coupling reactions and as a precursor to more complex heterocyclic systems.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, especially kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, leveraging its halogenated pyridine core.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in metal-catalyzed reactions.
• Material Science Research: Employed in the development of organic electronic materials and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Useful for synthesizing tagged molecules and probes for studying biological pathways.
• Custom Synthesis and Contract Manufacturing: A fundamental building block for custom synthesis projects requiring functionalized pyridine chemistry.

Basic Information

Product Name	2-Bromo-4-Pyridine Acetic Acid
CAS No.	183483-29-6
Molecular Formula	C7H6BrNO2
Molecular Weight	216.03 g/mol
Synonyms	(2-Bromo-4-pyridinyl)acetic Acid; 2-Bromo-4-pyridylacetic Acid; 2-(2-Bromopyridin-4-yl)acetic Acid; 4-Pyridineacetic Acid, 2-bromo-; α-Carboxy-2-bromo-4-picoline; 2-Bromo-4-picolylacetic Acid
EINECS	Contact for details

Quality Control

Our 2-Bromo-4-Pyridine Acetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.