Description

2-Pyridinecarboxaldehyde, 6-Ethynyl- (9Ci) is a versatile and highly functionalized pyridine derivative, serving as a critical building block in advanced organic synthesis. Its molecular architecture, featuring both an aldehyde and an ethynyl group, makes it an invaluable precursor for constructing complex heterocyclic systems and pharmaceutical intermediates. This compound is primarily sought after by research institutions and chemical manufacturers in the pharmaceutical, agrochemical, and material science sectors for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Development: Used in creating advanced active ingredients for crop protection products.
• Ligand Synthesis: Serves as a precursor for constructing sophisticated chelating ligands in catalysis and material science.
• Material Science Research: Employed in the development of organic semiconductors, metal-organic frameworks (MOFs), and other functional polymers.
• Cross-Coupling Reactions: The ethynyl group enables efficient Sonogashira and other palladium-catalyzed cross-coupling reactions.
• Academic & R&D: A valuable reagent for methodological development and exploring new chemical spaces in organic chemistry.

Basic Information

Product Name	2-Pyridinecarboxaldehyde, 6-Ethynyl- (9Ci)
CAS No.	183438-97-3
Molecular Formula	C8H5NO
Molecular Weight	131.13 g/mol
Synonyms	6-Ethynylpyridine-2-carboxaldehyde; 6-Ethynyl-2-pyridinecarboxaldehyde; 2-Formyl-6-ethynylpyridine; 6-Ethynylpicolinaldehyde; 6-Ethynyl-2-formylpyridine; 2-Pyridinecarboxaldehyde, 6-ethynyl-; 6-Ethynyl-2-pyridylcarboxaldehyde
EINECS	Contact for details

Quality Control

Every batch of 2-Pyridinecarboxaldehyde, 6-Ethynyl- (9Ci) is produced and tested under strict quality management protocols to ensure consistency and reliability for your research and production needs. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles as determined by advanced analytical techniques. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability and documentation excellence.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. Due to its sensitivity to oxidation and light, prolonged exposure to air or light should be avoided. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	Yellow to light brown solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.