Description

(S)-4-Ethyl-4-Hydroxy-8-Methoxy-3-Oxo-3,4-Dihydro-1H-Pyrano[3,4-C]Pyridine-6-Carboxylic Acid Propyl Ester is a high-purity, chiral synthetic intermediate of significant interest in advanced pharmaceutical research and development. Its complex fused pyranopyridine structure makes it a valuable building block for creating novel active pharmaceutical ingredients (APIs) with specific stereochemical requirements. This compound is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and fine chemical industries seeking to develop new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of novel drug candidates, particularly in therapeutic areas requiring high stereochemical purity.
• Active Pharmaceutical Ingredient (API) Development: Serves as a core scaffold or advanced intermediate in the research and process development of new APIs.
• Asymmetric Synthesis: Utilized in stereoselective chemical reactions to construct complex molecular architectures due to its defined (S)-configuration.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and lead optimization programs within drug discovery.
• Reference Standard: Used as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Fine Chemical Synthesis: Applied in the custom synthesis of specialized, high-value compounds for research and development purposes.

Basic Information

Product Name	(S)-4-Ethyl-4-Hydroxy-8-Methoxy-3-Oxo-3,4-Dihydro-1H-Pyrano[3,4-C]Pyridine-6-Carboxylic Acid Propyl Ester
CAS No.	183434-00-6
Molecular Formula	C16H19NO6
Molecular Weight	321.33 g/mol
Synonyms	(S)-4-Ethyl-4-hydroxy-8-methoxy-3-oxo-3,4-dihydro-1H-pyrano[3,4-c]pyridine-6-carboxylic acid propyl ester; Propyl (S)-4-ethyl-4-hydroxy-8-methoxy-3-oxo-3,4-dihydro-1H-pyrano[3,4-c]pyridine-6-carboxylate; (S)-enantiomer of the pyranopyridine propyl ester; 1H-Pyrano[3,4-c]pyridine-6-carboxylic acid, 3,4-dihydro-4-ethyl-4-hydroxy-8-methoxy-3-oxo-, propyl ester, (S)-; CAS 183434-00-6
EINECS	Contact for details

Quality Control

Our (S)-4-Ethyl-4-Hydroxy-8-Methoxy-3-Oxo-3,4-Dihydro-1H-Pyrano[3,4-C]Pyridine-6-Carboxylic Acid Propyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, ensuring full traceability and compliance with your research protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound may be light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.