Description

Methyl 1-Amino-1-Cyclooctanecarboxylate CAS NO 183429-68-7 is a specialized, high-purity amino acid ester derivative featuring a conformationally constrained cyclooctane ring. This unique structure makes it a valuable advanced pharmaceutical intermediate and a versatile chiral building block for complex organic synthesis. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting neurological and metabolic disorders.
• Chiral Building Block: Essential for constructing complex, stereochemically defined molecules in asymmetric synthesis for agrochemicals and specialty chemicals.
• Peptidomimetics Research: Used to introduce constrained, non-natural amino acid motifs into peptide analogs to enhance stability and biological activity.
• Ligand and Catalyst Development: Serves as a backbone for creating novel chelating ligands and organocatalysts in chemical process development.
• Academic & R&D: Employed in medicinal chemistry and organic synthesis research for method development and exploring new chemical spaces.

Basic Information

Product Name	Methyl 1-Amino-1-Cyclooctanecarboxylate
CAS No.	183429-68-7
Molecular Formula	C10H19NO2
Molecular Weight	185.26 g/mol
Synonyms	1-Amino-1-cyclooctanecarboxylic acid methyl ester; Methyl 1-aminocyclooctane-1-carboxylate; 1-Cyclooctylglycine methyl ester; 1-Amino-cyclooctanecarboxylic acid methyl ester; (1-Aminocyclooctyl)methyl carboxylate; Methyl α-aminocyclooctaneacetate; ACCM; Contact for additional trade names.
EINECS	Contact for details

Quality Control

Our Methyl 1-Amino-1-Cyclooctanecarboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and chiral purity analysis, to ensure it meets the high standards required for research and production. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.