Description

6-Amino-5-Methylnicotinonitrile is a versatile heterocyclic nitrile building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both amino and nitrile functional groups on a pyridine core, makes it a critical precursor for constructing complex pharmacophores and functional materials. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it serves as a key intermediate in the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and central nervous system (CNS) active compound research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, leveraging its heterocyclic structure for bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in catalytic processes and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of organic electronic materials and dyes due to its electron-accepting nitrile group and modifiable amino group.
• Chemical Biology Probes: Utilized as a scaffold for developing fluorescent tags and molecular probes for biological imaging and diagnostics.
• Academic & R&D: A valuable reagent for methodological studies in organic chemistry, including cross-coupling and cyclization reactions.

Basic Information

Product Name	6-Amino-5-Methylnicotinonitrile
CAS No.	183428-91-3
Molecular Formula	C7H7N3
Molecular Weight	133.15 g/mol
Synonyms	5-Methyl-6-aminonicotinonitrile; 3-Cyano-5-methyl-6-aminopyridine; 6-Amino-5-methyl-3-pyridinecarbonitrile; 5-Methyl-6-amino-3-cyanopyridine; 6-Amino-5-methylpyridine-3-carbonitrile; 3-Pyridinecarbonitrile, 6-amino-5-methyl-; 5-Methyl-6-aminopyridine-3-carbonitrile
EINECS	Contact for details

Quality Control

Our 6-Amino-5-Methylnicotinonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) detailing all specifications are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.