Description

Artesunate is a potent, water-soluble derivative of artemisinin, representing a cornerstone of modern antimalarial therapy. Its primary value lies in its rapid action against the blood stages of *Plasmodium falciparum* malaria, including severe and multidrug-resistant cases. This active pharmaceutical ingredient (API) is essential for manufacturers in the pharmaceutical industry producing injectable and oral formulations for global health programs, as well as for research institutions developing new therapeutic applications.

Application

• First-line treatment for severe malaria: Critical component in combination therapies (e.g., with amodiaquine, mefloquine) for intravenous or intramuscular administration.
• Pharmaceutical API manufacturing: Serves as the key active ingredient in the production of injectable solutions, tablets, and suppositories.
• Research and development: Used in pharmacological studies, mechanism of action research, and the development of novel artemisinin-based combination therapies (ACTs).
• Veterinary pharmaceuticals: Investigated for use in treating parasitic infections in animals.
• Reference standard: Employed as a high-purity analytical standard in quality control laboratories for drug testing and verification.

Basic Information

Product Name	Artesunate
CAS No.	182824-33-5
Molecular Formula	C19H28O8
Molecular Weight	384.42 g/mol
Synonyms	Artesunate; Dihydroartemisinin-12-α-succinate; Artesunic Acid; Arsumax; Artesunato; (+)-Artesunate; (3R,5aS,6R,8aS,9R,10S,12R,12aR)-Decahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin-10(3H)-one hydrogen succinate
EINECS	Contact for details

Quality Control

Our Artesunate is manufactured under strict quality management systems, targeting specifications that meet or exceed major pharmacopoeial standards such as USP and ICH guidelines. Every batch undergoes comprehensive analytical testing including HPLC for assay and related substances, residual solvent analysis, and specific identification tests. A detailed Certificate of Analysis (COA) is provided with each shipment to ensure full traceability and compliance with your quality requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption and degradation. For long-term storage, consider conditions under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any individual impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Specific Rotation	+12.0° to +14.0° (c = 1 in CHCl3)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.