Description

4-Chloro-3-Iodopicolinonitrile is a halogenated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a versatile intermediate in the development of complex molecules, particularly in pharmaceutical and agrochemical research. Industries that need it include pharmaceutical R&D for creating new active ingredients and agrochemical companies developing novel crop protection agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those targeting central nervous system disorders and infectious diseases.
• Agrochemical Synthesis: Used in the research and development of new herbicides and pesticides, leveraging its halogenated pyridine core.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis for cross-coupling reactions.
• Material Science Research: Employed in the synthesis of organic electronic materials and liquid crystals due to its electron-deficient aromatic system.
• Chemical Biology Probes: Useful for constructing molecular probes and tags for studying biological processes and target engagement.

Basic Information

Product Name	4-Chloro-3-Iodopicolinonitrile
CAS No.	182819-58-5
Molecular Formula	C6HClIN2
Molecular Weight	278.44 g/mol
Synonyms	3-Iodo-4-chloropicolinonitrile; 4-Chloro-3-iodopyridine-2-carbonitrile; 2-Cyano-4-chloro-3-iodopyridine; 4-Chloro-3-iodo-2-pyridinecarbonitrile; Picolinonitrile, 4-chloro-3-iodo-; 4-Chloro-3-iodo-2-cyanopyridine
EINECS	Contact for details

Quality Control

Our 4-Chloro-3-Iodopicolinonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.