Description

2-(Trifluoromethoxy)Phenyl Isocyanate is a specialized aromatic isocyanate monomer featuring a trifluoromethoxy substituent. This compound is valued for its role as a key building block in the synthesis of advanced polymers and agrochemicals, where it imparts unique chemical stability and performance characteristics. It is primarily sought by R&D chemists and process engineers in the pharmaceutical, agrochemical, and high-performance materials industries for creating novel ureas, carbamates, and polyurethane derivatives.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring the incorporation of a fluorinated aromatic moiety for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the production of modern herbicides, fungicides, and insecticides, where the trifluoromethoxy group contributes to improved lipophilicity and biological activity.
• Polymer & Material Science: Acts as a monomer for synthesizing specialized polyurethanes, polyureas, and coatings with tailored properties such as chemical resistance, weatherability, and low surface energy.
• Chemical Research & Development: Employed in academic and industrial R&D labs for exploring new reaction pathways and creating novel chemical entities with fluorinated aromatic components.
• Liquid Crystal & Electronic Materials: Utilized in the development of advanced organic materials for electronic applications, where its structural motif can influence dielectric properties and molecular alignment.

Basic Information

Product Name	2-(Trifluoromethoxy)Phenyl Isocyanate
CAS No.	182500-26-1
Molecular Formula	C8H4F3NO2
Molecular Weight	203.12 g/mol
Synonyms	1-Isocyanato-2-(trifluoromethoxy)benzene; 2-(Trifluoromethoxy)phenyl isocyanate; α,α,α-Trifluoro-o-cresyl isocyanate; o-(Trifluoromethoxy)phenyl isocyanate; 2-Trifluoromethoxyphenyl isocyanate; Isocyanic acid, 2-(trifluoromethoxy)phenyl ester; (2-Trifluoromethoxyphenyl)isocyanate
EINECS	Contact for details

Quality Control

Our 2-(Trifluoromethoxy)Phenyl Isocyanate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, assay, and impurity profiles. We support compliance with relevant regulatory frameworks, including REACH.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at temperatures between 2°C and 8°C (refrigerated) to maximize stability. This product is hygroscopic (moisture-sensitive) and should be handled under a dry inert atmosphere (e.g., nitrogen or argon) to prevent degradation. Keep away from heat, sparks, open flames, and strong bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.1%
Density (at 20°C)	~1.4 g/cm³

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.