Description

Carbamic Acid, (1-Oxo-2-Butynyl)-, 1,1-Dimethylethyl Ester (9Ci) is a specialized organic compound belonging to the class of carbamate esters, serving as a valuable protected intermediate or building block in advanced synthetic chemistry. Its molecular structure, featuring both a carbamate and an activated alkyne moiety, makes it a critical reagent for the controlled synthesis of complex molecules, particularly in pharmaceutical research and development. This compound is essential for chemists and manufacturers in the life sciences, agrochemical, and fine chemical industries who require high-purity, reliable intermediates for constructing novel active ingredients.

Application

This protected carbamate derivative is designed for sophisticated organic synthesis, primarily as a key intermediate. Its applications include:

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of active pharmaceutical ingredients (APIs), especially those requiring carbamate or alkyne functional groups.
• Peptidomimetic & Protease Inhibitor Research: Used in the development of peptide-like molecules and enzyme inhibitors, where the carbamate group can mimic peptide bonds.
• Agrochemical Synthesis: Acts as an intermediate in the creation of novel herbicides, fungicides, and insecticides that utilize carbamate chemistry.
• Material Science & Polymer Chemistry: Employed in the synthesis of specialty monomers or polymers with tailored properties, leveraging its reactive alkyne handle for "click chemistry" applications.
• Chemical Biology & Bioconjugation: Utilized as a reagent for labeling or modifying biomolecules due to its specific and controllable reactivity.

Basic Information

Product Name	Carbamic Acid, (1-Oxo-2-Butynyl)-, 1,1-Dimethylethyl Ester (9Ci)
CAS No.	182495-32-5
Molecular Formula	C9H13NO3
Molecular Weight	183.20 g/mol
Synonyms	tert-Butyl (1-oxo-2-butyn-1-yl)carbamate; N-(1-Oxo-2-butynyl)carbamic Acid tert-Butyl Ester; BOC-Protected 2-Butynoic Acid Amide; tert-Butoxycarbonylamino(2-butynoyl); (1-Oxo-2-butynyl)carbamic Acid tert-Butyl Ester; Carbamic acid, N-(1-oxo-2-butynyl)-, 1,1-dimethylethyl ester; BOC-2-Butynoylamide
EINECS	Contact for details

Quality Control

Our production of Carbamic Acid, (1-Oxo-2-Butynyl)-, 1,1-Dimethylethyl Ester adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and GC for residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes. We support compliance with REACH and other relevant global regulatory frameworks for chemical substances.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5% w/w
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.