Description

5-Aminomethyl-Pyridine-2-Carbonitrile is a versatile and high-value pyridine derivative, serving as a critical building block in advanced organic synthesis. Its bifunctional structure, featuring both an aminomethyl and a nitrile group, makes it an essential precursor for constructing complex heterocyclic systems and active pharmaceutical ingredients (APIs). This compound is particularly valuable for research and development chemists and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of various drug candidates, particularly those targeting the central nervous system (CNS) and as kinase inhibitors.
• Agrochemical Synthesis: Used in the development of novel pesticides and herbicides, leveraging the pyridine core for bioactivity.
• Ligand and Catalyst Preparation: Serves as a precursor for chelating ligands in coordination chemistry and catalysis.
• Material Science Research: Employed in the synthesis of functionalized polymers and advanced organic materials.
• Chemical Biology Probes: Useful for creating molecular probes and tags due to its reactive functional groups.
• Custom Synthesis and R&D: A valuable starting material for contract research organizations (CROs) and fine chemical companies engaged in custom synthesis projects.

Basic Information

Product Name	5-Aminomethyl-Pyridine-2-Carbonitrile
CAS No.	182291-88-9
Molecular Formula	C7H7N3
Molecular Weight	133.15 g/mol
Synonyms	2-Cyano-5-(aminomethyl)pyridine; (2-Cyano-5-pyridinyl)methanamine; 5-(Aminomethyl)picolinonitrile; 5-(Aminomethyl)-2-pyridinecarbonitrile; 2-Pyridinecarbonitrile, 5-(aminomethyl)-; 5-Aminomethyl-2-cyanopyridine; 5-Pyridinemethanamine, 2-cyano-
EINECS	Contact for details

Quality Control

Our 5-Aminomethyl-Pyridine-2-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture. We provide a Certificate of Analysis (COA) with every shipment, ensuring full traceability and compliance with your research or production specifications. Our quality commitment supports applications requiring high-purity intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if necessary to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.