Description

2-Iodo-6-Methoxy-Pyridine is a versatile halogenated pyridine derivative, a crucial building block in advanced organic synthesis. Its value lies in the strategic positioning of iodine and methoxy groups, which enable efficient cross-coupling reactions and functional group transformations. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries, serving as a key intermediate in the development of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of complex drug candidates, particularly for kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the development of novel pesticides and herbicides, leveraging its reactivity for constructing heterocyclic cores.
• Material Science Precursor: Serves as a building block for creating functionalized ligands, organic semiconductors, and liquid crystal materials.
• Cross-Coupling Reactions: The iodine atom makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Stille, and Negishi couplings to form new carbon-carbon bonds.
• Chemical Research & Development: A valuable reagent for medicinal chemistry and process chemistry for exploring new synthetic pathways.
• Ligand Synthesis: Used to prepare specialized nitrogen-containing ligands for catalysis and coordination chemistry.

Basic Information

Product Name	2-Iodo-6-Methoxy-Pyridine
CAS No.	182275-70-3
Molecular Formula	C6H6INO
Molecular Weight	235.02 g/mol
Synonyms	6-Methoxy-2-iodopyridine; 2-Iodo-6-methoxypyridine; 6-Methoxy-2-pyridinyl iodide; 2-Iodo-6-pyridinol methyl ether; 2-Iodo-6-methoxypyridine; Pyridine, 2-iodo-6-methoxy-; 182275-70-3; 6-Methoxypyridin-2-yl iodide
EINECS	Contact for details

Quality Control

Our 2-Iodo-6-Methoxy-Pyridine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements of research and industrial-scale synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residue on Ignition	< 0.1%
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.