Description

3,5-Bis(tert-Butyldiphenylsilyloxy)Benzyl Alcohol is a high-value, protected benzyl alcohol derivative featuring two tert-butyldiphenylsilyl (TBDPS) ether groups, making it a crucial advanced intermediate in complex organic synthesis. Its primary value lies in its role as a versatile building block for constructing sophisticated molecular architectures, particularly in pharmaceutical research and fine chemical manufacturing. This compound is essential for chemists and R&D teams in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity, functionalized intermediates for developing active pharmaceutical ingredients (APIs) and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key protected synthon in the multi-step synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Organic Synthesis Building Block: Used in constructing complex molecules for medicinal chemistry, leveraging the orthogonal protecting group strategy of TBDPS ethers.
• Agrochemical Research: Serves as a precursor in the development of novel herbicides, fungicides, and plant growth regulators.
• Material Science: Potential monomer or cross-linking agent in the synthesis of specialty polymers and advanced organic materials.
• Academic & R&D Laboratories: A valuable reagent for methodological development in synthetic organic chemistry and catalysis studies.
• Peptide & Nucleotide Chemistry: Can be utilized in the synthesis of modified biomolecules where selective protection of hydroxyl groups is required.

Basic Information

Item	Details
Product Name	3,5-Bis(tert-Butyldiphenylsilyloxy)Benzyl Alcohol
CAS No.	182250-70-0
Molecular Formula	C39H44O3Si2
Molecular Weight	617.0 g/mol (approx.)
Synonyms	3,5-Bis[(1,1-dimethylethyl)di phenylsilyloxy]benzenemethanol; Benzyl alcohol, 3,5-bis[(1,1-dimethylethyl)diphenylsilyloxy]-; 3,5-Bis(TBDPS-oxy)benzyl alcohol; 3,5-Di-O-(tert-butyldiphenylsilyl)benzyl alcohol; 3,5-Bis(tert-butyldiphenylsiloxy)benzyl alcohol; TBDPS-protected benzyl alcohol derivative; 182250-70-0
EINECS	Contact for details

Quality Control

Our 3,5-Bis(tert-Butyldiphenylsilyloxy)Benzyl Alcohol is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and commercial synthesis. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.