Description

3,5-Bis(tert-Butyldiphenylsilyloxy)Benzoic Acid Methyl Ester is a high-purity, protected benzoic acid derivative designed for advanced synthetic chemistry. This compound is a critical building block in the synthesis of complex organic molecules, offering robust protection for phenolic hydroxyl groups under demanding reaction conditions. It is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries who require reliable, high-quality intermediates for multi-step synthesis and process development.

Application

• Pharmaceutical Intermediate: Key protected synthon in the multi-step synthesis of active pharmaceutical ingredients (APIs), particularly for compounds with complex phenolic architectures.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators requiring selective deprotection strategies.
• Ligand and Catalyst Development: Serves as a precursor for sophisticated ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Polymer and Material Science: Building block for high-performance polymers, dendrimers, and specialty monomers where controlled functionalization is required.
• Organic Synthesis Research: A versatile reagent in academic and industrial R&D for exploring new synthetic methodologies and protecting group strategies.
• Fine Chemical Production: Intermediate in the manufacture of complex fragrances, dyes, and other specialty fine chemicals.

Basic Information

Item	Details
Product Name	3,5-Bis(tert-Butyldiphenylsilyloxy)Benzoic Acid Methyl Ester
CAS No.	182250-68-6
Molecular Formula	C41H46O4Si2
Molecular Weight	659.0 g/mol
Synonyms	Methyl 3,5-Bis[(tert-butyldiphenylsilyl)oxy]benzoate; Benzoic acid, 3,5-bis[(1,1-dimethylethyl)di phenylsilyl]oxy]-, methyl ester; 3,5-Di-O-(tert-butyldiphenylsilyl) Methyl Benzoate; Methyl 3,5-di-O-(t-butyldiphenylsilyl)benzoate; TBDPS-protected Methyl 3,5-Dihydroxybenzoate; 3,5-Bis(TBDPS-oxy) Methyl Benzoate
EINECS	Contact for details

Quality Control

Every batch of 3,5-Bis(tert-Butyldiphenylsilyloxy)Benzoic Acid Methyl Ester undergoes rigorous analytical testing to ensure it meets the stringent purity requirements for advanced synthetic applications. Our quality assurance process includes validated methods such as HPLC, NMR, and GC-MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.