Description

(S)-(-)-2-Benzylsuccinic Acid 1-Methyl Ester is a high-purity chiral building block and synthetic intermediate of significant importance in advanced organic synthesis. Its value lies in its defined stereochemistry, which is critical for producing optically active compounds with specific biological or material properties. This product is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require enantiomerically pure intermediates for drug discovery, process development, and the synthesis of fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of active pharmaceutical ingredients (APIs), particularly in programs targeting enzymes or receptors sensitive to stereochemistry.
• Asymmetric Synthesis: Used as a starting material or intermediate in catalytic asymmetric reactions to construct complex molecular architectures.
• Agrochemical Research: Employed in the synthesis of novel, enantiomerically pure herbicides, fungicides, or plant growth regulators.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands used in transition metal catalysis.
• Fine Chemical Production: Integral to the multi-step synthesis of specialty chemicals, flavors, and fragrances where optical purity is a requirement.
• Academic & R&D: A valuable compound for methodological studies in organic chemistry and for training purposes in advanced synthetic laboratories.

Basic Information

Product Name	(S)-(-)-2-Benzylsuccinic Acid 1-Methyl Ester
CAS No.	182247-45-6
Molecular Formula	C13H16O4
Molecular Weight	236.26 g/mol
Synonyms	(S)-2-Benzylsuccinic Acid 1-Methyl Ester; (S)-(-)-Methyl 2-Benzylsuccinate; (S)-Methyl 2-Benzylbutanedioate; (2S)-2-Benzyl-4-methoxy-4-oxobutanoic Acid; 1-Methyl (S)-2-Benzylsuccinate; (S)-2-Benzyl-1-methoxy-1-oxobutan-1,4-dioate; L-2-Benzylsuccinic Acid Methyl Ester
EINECS	Contact for details

Quality Control

Our production of (S)-(-)-2-Benzylsuccinic Acid 1-Methyl Ester adheres to stringent quality protocols to ensure batch-to-batch consistency and high enantiomeric purity. Each lot is characterized using advanced analytical techniques including chiral HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, chiral excess, and impurity profile is provided with every shipment, supporting compliance with cGMP and ISO standards for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The product may be moisture-sensitive; keep the container tightly sealed under an inert atmosphere if specified.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% e.e.
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.