Description

2-Mesyl-4-Picoline is a high-purity chemical intermediate characterized by its mesylate (methanesulfonate) functional group attached to a methylpyridine core. This compound is valued for its role as a versatile building block in advanced organic synthesis, particularly in the construction of complex pharmaceutical molecules and specialized agrochemicals. It is essential for research and development chemists and process engineers in the pharmaceutical, agrochemical, and fine chemical industries seeking to introduce sulfonate ester moieties with precision.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of active pharmaceutical ingredients (APIs), especially for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the pyridine scaffold for bioactivity.
• Ligand and Catalyst Preparation: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and transition metal complexes.
• Material Science Research: Employed in the development of organic electronic materials and advanced polymers where the mesylate group acts as a reactive handle.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up processes under cGMP or ISO standards.
• Academic and R&D Laboratories: Used in methodological development and exploratory chemistry for new reaction pathways.

Basic Information

Product Name	2-Mesyl-4-Picoline
CAS No.	182233-57-4
Molecular Formula	C8H11NO3S
Molecular Weight	201.24 g/mol
Synonyms	4-Methyl-2-pyridinemethanol methanesulfonate; 2-(Methanesulfonyloxy)methyl-4-methylpyridine; 4-Methyl-2-(methylsulfonyloxy)methylpyridine; 2-Mesyloxymethyl-4-picoline; 2-(Methylsulfonyloxymethyl)-4-methylpyridine; 4-Picoline-2-methanol methanesulfonate; 2-Hydroxymethyl-4-methylpyridine methanesulfonate
EINECS	Contact for details

Quality Control

Every batch of 2-Mesyl-4-Picoline is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high standards required for sensitive synthetic applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment. Our quality protocols are designed to support regulatory filings in target industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.