Description

8-Chloro-2-Chloromethyl-6-Trifluoromethyl-Imidazo[1,2-A]Pyridine is a high-value, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its unique molecular architecture, which incorporates halogen and trifluoromethyl substituents on an imidazopyridine scaffold, enabling precise structural modifications. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients. Its specific reactivity profile makes it an essential intermediate for developing compounds with potential biological activity.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, infectious diseases, or oncology.
• Agrochemical Synthesis: Serves as a crucial building block for creating novel herbicides, fungicides, or insecticides, leveraging the bioactivity-enhancing properties of the trifluoromethyl and halogen groups.
• Material Science Research: Used in the development of advanced organic materials, such as ligands for catalysts or components for organic electronic devices.
• Chemical Biology Probes: Employed in the synthesis of molecular probes for studying biological pathways and target engagement due to its modifiable structure.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for use in client-specific, multi-step synthetic routes.

Basic Information

Product Name	8-Chloro-2-Chloromethyl-6-Trifluoromethyl-Imidazo[1,2-A]Pyridine
CAS No.	182181-31-3
Molecular Formula	C9H5Cl2F3N2
Molecular Weight	269.05 g/mol
Synonyms	2-(Chloromethyl)-8-chloro-6-(trifluoromethyl)imidazo[1,2-a]pyridine; 8-Chloro-2-chloromethyl-6-trifluoromethylimidazo[1,2-a]pyridine; Imidazo[1,2-a]pyridine, 8-chloro-2-(chloromethyl)-6-(trifluoromethyl)-; 182181-31-3; 8-Chloro-2-(chloromethyl)-6-(trifluoromethyl)imidazo[1,2-a]pyridine
EINECS	Contact for details

Quality Control

Our 8-Chloro-2-Chloromethyl-6-Trifluoromethyl-Imidazo[1,2-A]Pyridine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for research and process development. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with each shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.