Description

2-Mercapto-6-Methyl-4-(Trifluoromethyl)Nicotinonitrile is a high-value, multi-functional heterocyclic building block. This compound is critical for the synthesis of advanced pharmaceutical intermediates and agrochemicals due to its unique trifluoromethyl and mercapto substituents. It is primarily required by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the development of advanced herbicides and pesticides, leveraging the bioactivity of the trifluoromethylpyridine core.
• Material Science Precursor: Serves as a precursor for ligands and functional molecules used in catalysis and advanced materials.
• Chemical Research & Development: A versatile scaffold for medicinal chemistry and structure-activity relationship (SAR) studies in academic and industrial labs.

Basic Information

Product Name	2-Mercapto-6-Methyl-4-(Trifluoromethyl)Nicotinonitrile
CAS No.	182127-92-0
Molecular Formula	C8H5F3N2S
Molecular Weight	218.20 g/mol
Synonyms	6-Methyl-4-(trifluoromethyl)-2-mercaptonicotinonitrile; 2-Mercapto-6-methyl-4-(trifluoromethyl)pyridine-3-carbonitrile; 4-(Trifluoromethyl)-6-methyl-2-thioxo-1,2-dihydropyridine-3-carbonitrile; 2-Thioxo-1,2-dihydro-6-methyl-4-(trifluoromethyl)nicotinonitrile; 2-Mercapto-6-methyl-4-trifluoromethyl-3-cyanopyridine
EINECS	Contact for details

Quality Control

Our 2-Mercapto-6-Methyl-4-(Trifluoromethyl)Nicotinonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and LC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its light-sensitive nature and propensity to be easily oxidized, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.