Description

Methyl 1H-Pyrazole-4-Carboxylate Hydrochloride is a high-purity, pharmaceutically relevant chemical building block, primarily used as a key intermediate in the synthesis of active pharmaceutical ingredients (APIs). This compound is critical for research and development in medicinal chemistry, offering a versatile pyrazole core for constructing complex molecules. It is essential for manufacturers and R&D laboratories in the pharmaceutical, agrochemical, and fine chemical sectors seeking reliable, high-quality intermediates for advanced synthesis.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging the pyrazole moiety for biological activity.
• Chemical Research & Development: Serves as a versatile scaffold in academic and industrial R&D for exploring new chemical entities and reaction pathways.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, dyes, and complex organic compounds requiring a functionalized pyrazole structure.
• Ligand and Catalyst Preparation: Useful for synthesizing specialized ligands for metal catalysis and coordination chemistry applications.

Basic Information

Product Name	Methyl 1H-Pyrazole-4-Carboxylate Hydrochloride
CAS No.	181997-36-4
Molecular Formula	C5H7N2O2·HCl
Molecular Weight	162.58 g/mol
Synonyms	1H-Pyrazole-4-carboxylic acid, methyl ester, hydrochloride; Methyl pyrazole-4-carboxylate hydrochloride; 4-(Methoxycarbonyl)-1H-pyrazole hydrochloride; Methyl 4-pyrazolecarboxylate hydrochloride; 1H-Pyrazole-4-carboxylic acid methyl ester HCl; 4-Carbomethoxy-1H-pyrazole hydrochloride; Pyrazole-4-carboxylic acid methyl ester hydrochloride
EINECS	Contact for details

Quality Control

Our Methyl 1H-Pyrazole-4-Carboxylate Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, detailing key parameters such as assay, impurity profile, and physical characteristics. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.