Description

(R)-1-(Pyridin-4-Yl)Pyrrolidin-3-Ol CAS NO 181959-78-4 is a high-purity chiral pyrrolidine derivative, serving as a critical building block in modern asymmetric synthesis. Its value lies in its role as a versatile intermediate for constructing complex molecules with defined stereochemistry, essential for developing active pharmaceutical ingredients (APIs). This compound is primarily needed by research institutions and pharmaceutical companies engaged in the discovery and process development of new therapeutic agents, particularly in areas requiring sophisticated chiral scaffolds.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel drug candidates, especially for central nervous system (CNS) and antiviral therapies.
• Asymmetric Catalysis Ligand Precursor: Used in the synthesis of chiral ligands for metal-catalyzed reactions, enabling the production of enantiomerically pure compounds.
• Agrochemical Research: Employed in the development of advanced, stereospecific pesticides and herbicides where biological activity is chirality-dependent.
• Academic & R&D Laboratories: Serves as a standard or starting material for methodological studies in organic and medicinal chemistry.
• Process Chemistry Development: Utilized for scaling up synthetic routes and optimizing manufacturing processes for chiral APIs.

Basic Information

Product Name	(R)-1-(Pyridin-4-Yl)Pyrrolidin-3-Ol
CAS No.	181959-78-4
Molecular Formula	C9H12N2O
Molecular Weight	164.21 g/mol
Synonyms	(R)-1-(4-Pyridyl)-3-pyrrolidinol; (3R)-1-(4-Pyridinyl)-3-pyrrolidinol; (R)-3-Hydroxy-1-(pyridin-4-yl)pyrrolidine; (R)-1-(4-Pyridinyl)-3-pyrrolidinol; Pyrrolidin-3-ol, 1-(4-pyridinyl)-, (3R)-; (R)-1-(Pyridin-4-yl)pyrrolidin-3-ol; (R)-N-(4-Pyridyl)-3-hydroxypyrrolidine
EINECS	Contact for details

Quality Control

Our (R)-1-(Pyridin-4-Yl)Pyrrolidin-3-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with exacting standards for research and development use. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.