Description

1-Cyclobutenecarboxylic Acid Ethyl Ester is a specialized, high-value organic building block featuring a strained cyclobutene ring system. This compound matters as a versatile synthon in advanced organic synthesis, enabling the construction of complex molecular architectures through ring-opening and functionalization reactions. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those requiring strained-ring scaffolds for biological activity.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides with unique modes of action.
• Material Science Research: Acts as a monomer or cross-linking agent in the development of novel polymers with specific thermal or mechanical properties.
• Organic Synthesis Building Block: Employed in [4+2] cycloaddition (Diels-Alder) reactions and other ring transformations to create complex, polycyclic structures.
• Ligand and Catalyst Development: Utilized for the preparation of specialized ligands for asymmetric catalysis and organometallic chemistry.
• Flavor and Fragrance Industry: Potential intermediate for the synthesis of unique aroma chemicals with complex cyclic backbones.

Basic Information

Product Name	1-Cyclobutenecarboxylic Acid Ethyl Ester
CAS No.	181941-46-8
Molecular Formula	C7H10O2
Molecular Weight	126.15 g/mol
Synonyms	Ethyl 1-Cyclobutene-1-carboxylate; Ethyl Cyclobutene-1-carboxylate; 1-Cyclobutene-1-carboxylic Acid Ethyl Ester; Cyclobut-1-ene-1-carboxylic Acid Ethyl Ester; Ethyl Cyclobut-1-ene-1-carboxylate; 1-Carbethoxycyclobutene; Cyclobutene-1-carboxylic Acid Ethyl Ester
EINECS	Contact for details

Quality Control

Our 1-Cyclobutenecarboxylic Acid Ethyl Ester is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including GC/HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. The container should be kept tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.