Description

Pyrrolo[1,2-A]Pyrazine-3-Carboxylic Acid, Octahydro-, Methyl Ester, (3R-Trans)- (9Ci) is a high-purity, stereochemically defined heterocyclic building block of significant interest in advanced organic synthesis. Its value lies in its rigid, fused bicyclic structure and functional group handles, which are critical for constructing complex molecular architectures with precise three-dimensional control. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries, where it serves as a key intermediate in the discovery and development of new active ingredients.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and antiviral research.
• Agrochemical Synthesis: Used in the development of advanced, stereoselective pesticides and herbicides where specific spatial orientation is required for biological activity.
• Chemical Biology & Probe Development: Employed as a scaffold for creating molecular probes to study enzyme function and biological pathways.
• Asymmetric Catalysis Research: Serves as a precursor or ligand in the development of new chiral catalysts for stereoselective transformations.
• Material Science Precursor: Potential use in the synthesis of specialized organic electronic materials or advanced polymers with unique properties.

Basic Information

Product Name	Pyrrolo[1,2-A]Pyrazine-3-Carboxylic Acid, Octahydro-, Methyl Ester, (3R-Trans)- (9Ci)
CAS No.	181795-67-5
Molecular Formula	C9H14N2O2
Molecular Weight	182.22 g/mol
Synonyms	(3R-trans)-Octahydropyrrolo[1,2-a]pyrazine-3-carboxylic acid methyl ester; Methyl (3R,8aS)-octahydropyrrolo[1,2-a]pyrazine-3-carboxylate; (3R-trans)-Methyl octahydropyrrolo[1,2-a]pyrazine-3-carboxylate; (3R,8aS)-Hexahydro-1H-pyrrolo[1,2-a]pyrazine-3-carboxylic acid, methyl ester; Pyrrolo[1,2-a]pyrazine-3-carboxylic acid, octahydro-, methyl ester, (3R-trans)-; 181795-67-5; (3R,8aS)-Methyl octahydropyrrolo[1,2-a]pyrazine-3-carboxylate
EINECS	Contact for details

Quality Control

Our production of Pyrrolo[1,2-A]Pyrazine-3-Carboxylic Acid, Octahydro-, Methyl Ester, (3R-Trans)- (9Ci) adheres to stringent quality management protocols to ensure batch-to-batch consistency and high chemical purity. Each lot undergoes comprehensive analytical characterization, including chiral purity verification, to meet the exacting standards required for pharmaceutical R&D. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); therefore, containers should be kept sealed under an inert atmosphere when not in use to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.